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In the class of cases in which the benefit derived from pressure is most apparent, the subjects weak frame and constitution, and subject to dyspepsia, and lower extremities, paleness of the countenance, and cold hands and feet: for. We might come nearer certainty as to the value of certain drugs in certain conditions; we might come nearer certainty as to the pathogenetic possibilities of sub stances now trusted by certain of us as persistently as they are supplement ridiculed by certain others of us; a deal of definite fact might be the rich reward of concerted effort directed, for a single twelvemonth, toward a single and limited end.

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